For research use only. Not for therapeutic Use.
Sucralfate（Cat No.:A000025）is a gastroprotective agent used primarily in the treatment of ulcers, particularly peptic and duodenal ulcers. It works by forming a protective barrier over ulcer sites, binding to proteins in damaged mucosal tissue, which shields the area from acid, bile, and enzymes. This local action aids in healing and provides symptom relief without significant systemic absorption. Sucralfate is also studied for its potential benefits in treating esophagitis and other gastrointestinal conditions. Its unique mechanism and safety profile make it valuable in both clinical and research settings.
| Catalog Number | A000025 |
| CAS Number | 54182-58-0 |
| Synonyms | Antepsin; Sucralafate; Sucralfate |
| Molecular Formula | C12H54Al16O75S8 |
| Purity | ≥95% |
| Target | Bacterial |
| Storage | Store at -20°C |
| IUPAC Name | C([C@@H]1[C@H]([C@@H]([C@H]([C@H](O1)O[C@]2([C@H]([C@@H]([C@H](O2)COS(=O)(=O)O[Al])OS(=O)(=O)O[Al])OS(=O)(=O)O[Al])COS(=O)(=O)O[Al])OS(=O)(=O)O[Al])OS(=O)(=O)O[Al])OS(=O)(=O)O[Al])OS(=O)(=O)O[Al].O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.O.[Al].[Al].[Al].[Al].[Al].[Al].[Al].[Al] |
| InChI | InChI=1S/C12H22O35S8.16Al.32H2O/c13-48(14,15)37-1-4-6(43-51(22,23)24)8(45-53(28,29)30)9(46-54(31,32)33)11(40-4)42-12(3-39-50(19,20)21)10(47-55(34,35)36)7(44-52(25,26)27)5(41-12)2-38-49(16,17)18;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;/h4-11H,1-3H2,(H,13,14,15)(H,16,17,18)(H,19,20,21)(H,22,23,24)(H,25,26,27)(H,28,29,30)(H,31,32,33)(H,34,35,36);;;;;;;;;;;;;;;;;32*1H2/q;;;;;;;;;8*+1;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;/p-8/t4-,5-,6-,7-,8+,9-,10+,11-,12+;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;/m1................................................/s1 |
| InChIKey | IRIPCXKKNOWLLY-PIPKHVHYSA-F |
| Reference | 1: Hameeteman W. Clinical studies of sucralfate in reflux esophagitis. The European experience. J Clin Gastroenterol. 1991;13 Suppl 2:S16-20. Review. PubMed PMID: 1885899.<br /> |
