Sufosfamide

For research use only. Not for therapeutic Use.

  • CAT Number: I036766
  • CAS Number: 37753-10-9
  • Molecular Formula: C8H18ClN2O5PS
  • Molecular Weight: 320.72
  • Purity: 98%
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Sufosfamide is a biochemical with immunosuppressive activity stronger than cyclophosphamide.


Catalog Number I036766
CAS Number 37753-10-9
Synonyms

ASTA 5122; Sufosfamide

Molecular Formula C8H18ClN2O5PS
Purity 98%
Solubility Soluble in DMSO
Appearance Solid powder
Storage Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
IUPAC Name 2-((3-(2-chloroethyl)-2-oxido-1,3,2-oxazaphosphinan-2-yl)amino)ethyl methanesulfonate
InChI InChI=1S/C8H18ClN2O5PS/c1-18(13,14)16-8-4-10-17(12)11(6-3-9)5-2-7-15-17/h2-8H2,1H3,(H,10,12)
InChIKey ZSZKJARKHWCBJK-UHFFFAOYSA-N
SMILES CS(=O)(=O)OCCNP1(=O)OCCCN1CCCl
Reference

1. Arita C, Kaibara N, Hotokebuchi T, Takagishi K, Arai K. Effect of cyclophosphamide and its analogs on collagen arthritis in rats. Clin Immunol Immunopathol. 1987 Jun;43(3):354-61. doi: 10.1016/0090-1229(87)90145-0. PMID: 3581517.
2. Brock N, Stekar J, Pohl J, Niemeyer U, Scheffler G. Acrolein, the causative factor of urotoxic side-effects of cyclophosphamide, ifosfamide, trofosfamide and sufosfamide. Arzneimittelforschung. 1979;29(4):659-61. PMID: 114192.

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