Sulbactam sodium

• CAT Number: A000246
• CAS Number: 69388-84-7
• Molecular Formula: C8H10NNaO5S
• Molecular Weight: 255.22
• Purity: ≥95%
• Synonyms: CP-45899-2
• Target: Bacterial
• Storage: 3 years -20C powder
• IUPAC Name: sodium;(2S,5R)-3,3-dimethyl-4,4,7-trioxo-4lambda6-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
• InChI: InChI=1S/C8H11NO5S.Na/c1-8(2)6(7(11)12)9-4(10)3-5(9)15(8,13)14;/h5-6H,3H2,1-2H3,(H,11,12);/q;+1/p-1/t5-,6+;/m1./s1
• InChIKey: NKZMPZCWBSWAOX-IBTYICNHSA-M
• SMILES: CC1([C@@H](N2[C@H](S1(=O)=O)CC2=O)C(=O)[O-])C.[Na+]

Sulbactam sodium（Cat No.:A000246）is a beta-lactamase inhibitor used in combination with beta-lactam antibiotics to enhance their antimicrobial efficacy. It works by binding to and inactivating beta-lactamase enzymes produced by resistant bacteria, thus preventing the degradation of beta-lactam antibiotics. Sulbactam sodium is commonly used to treat infections caused by beta-lactamase-producing organisms, including respiratory, urinary tract, and intra-abdominal infections. It is particularly effective against Gram-negative bacteria, including Haemophilus influenzae and Escherichia coli. This combination therapy improves the spectrum and effectiveness of antibiotics, combating drug-resistant infections.

Reference

/Sulbactam Sodium./ Chemical Book. N.p., 2010. Web. 23 Aug. 2012./Ogawa Y. and Mii M., Screening for highly active Ë-lactam antibiotics against Agrobacterium tumefaciens. Arch Microbiol, Vol. 181, pp. 331-336, 2004.