For research use only. Not for therapeutic Use.
Sulfacetamide（Cat No.:R015646）is a sulfonamide antimicrobial agent commonly used in the treatment of bacterial eye infections, acne, and other skin conditions. It works by inhibiting the synthesis of folic acid in bacteria, preventing their growth and reproduction. Sulfacetamide is often formulated in topical creams, lotions, or eye drops for local application. It is known for its effectiveness in treating acne vulgaris, seborrheic dermatitis, and blepharitis. While generally well-tolerated, sulfacetamide can cause skin irritation or allergic reactions in some individuals. It is essential to follow medical guidance for appropriate use.
| Catalog Number | R015646 |
| CAS Number | 144-80-9 |
| Synonyms | N-[(4-aminophenyl)sulfonyl]acetamide; 4-(Acetylaminosulfonyl)aniline; A 500; Acetocid; Acetosulfamin; Acetosulfamine; Albamine; Albucid; Alesten; Formosulfacetamide; N-(4-Aminobenzenesulfonyl)acetamide; N-(p-Aminophenylsulfonyl)acetamide; N-Acetylsu |
| Molecular Formula | C8H10N2O3S |
| Purity | ≥95% |
| Target | Bacterial |
| Storage | -20°C |
| IUPAC Name | N-(4-aminophenyl)sulfonylacetamide |
| InChI | InChI=1S/C8H10N2O3S/c1-6(11)10-14(12,13)8-4-2-7(9)3-5-8/h2-5H,9H2,1H3,(H,10,11) |
| InChIKey | SKIVFJLNDNKQPD-UHFFFAOYSA-N |
| SMILES | CC(=O)NS(=O)(=O)C1=CC=C(C=C1)N |
| Reference | </br>1:Transport of sulfacetamide and levofloxacin in granular porous media under various conditions: Experimental observations and model simulations. Dong S, Gao B, Sun Y, Shi X, Xu H, Wu J, Wu J.Sci Total Environ. 2016 Dec 15;573:1630-1637. doi: 10.1016/j.scitotenv.2016.09.164. Epub 2016 Sep 29. PMID: 27692941 </br>2:Synthesis, characterization, theoretical prediction of activities and evaluation of biological activities of some sulfacetamide based hydroxytriazenes. Agarwal S, Baroliya PK, Bhargava A, Tripathi IP, Goswami AK.Bioorg Med Chem Lett. 2016 Jun 15;26(12):2870-3. doi: 10.1016/j.bmcl.2016.04.051. Epub 2016 Apr 19. PMID: 27136718 </br>3:The use of sodium sulfacetamide in dermatology. Wolf K, Silapunt S.Cutis. 2015 Aug;96(2):128-30. PMID: 26367751 </br>4:Carbon nanotube embedded poly 1,5-diaminonapthalene modified pyrolytic graphite sensor for the determination of sulfacetamide in pharmaceutical formulations. Yadav SK, Choubey PK, Agrawal B, Goyal RN.Talanta. 2014 Jan;118:96-103. doi: 10.1016/j.talanta.2013.09.061. Epub 2013 Oct 10. PMID: 24274275 </br>5:The use of sodium sulfacetamide 10%-sulfur 5% emollient foam in the treatment of acne vulgaris. Del Rosso JQ.J Clin Aesthet Dermatol. 2009 Aug;2(8):26-9. PMID: 20729951 Free PMC Article</br>6:The multifunctionality of 10% sodium sulfacetamide, 5% sulfur emollient foam in the treatment of inflammatory facial dermatoses. Draelos ZD.J Drugs Dermatol. 2010 Mar;9(3):234-6. PMID: 20232584 </br>7:Pharmacokinetic study on the mechanism of interaction of sulfacetamide sodium with bovine serum albumin: a spectroscopic method. Naik PN, Chimatadar SA, Nandibewoor ST.Biopharm Drug Dispos. 2010 Mar;31(2-3):120-8. doi: 10.1002/bdd.696. PMID: 20073032 </br>8:Sulfacetamide loaded Eudragit® RL100 nanosuspension with potential for ocular delivery. Mandal B, Alexander KS, Riga AT.J Pharm Pharm Sci. 2010;13(4):510-23. PMID: 21486528 Free Article</br>9:Interaction of topical sulfacetamide and topical dapsone with benzoyl peroxide. Dubina MI, Fleischer AB Jr.Arch Dermatol. 2009 Sep;145(9):1027-9. doi: 10.1001/archdermatol.2009.186. PMID: 19770443 </br>10:Treatment of papulopustular rosacea with sodium sulfacetamide 10%/sulfur 5% emollient foam. Trumbore MW, Goldstein JA, Gurge RM.J Drugs Dermatol. 2009 Mar;8(3):299-304. PMID: 19271381 |
