For research use only. Not for therapeutic Use.
Sulfadoxine-d3 (CAS: 1262770-70-6), a premium pharmaceutical research compound designed for advanced anti-malarial studies. As a deuterated analog of Sulfadoxine, it offers enhanced stability and improved pharmacokinetic properties. Sulfadoxine-d3 is ideal for use in pharmacological and biochemical research, providing precise and reliable data for your studies. This high-purity compound ensures consistent results, aiding in the development of novel anti-malarial therapies. Trusted by leading laboratories, Sulfadoxine-d3 is your go-to solution for cutting-edge malaria research. Unlock new possibilities in malaria treatment with Sulfadoxine-d3, where innovation meets reliability.
| Catalog Number | S000246 |
| CAS Number | 1262770-70-6 |
| Molecular Formula | C12H11D3N4O4S |
| Purity | ≥95% |
| Target | Parasite |
| IUPAC Name | 4-amino-N-[5-methoxy-6-(trideuteriomethoxy)pyrimidin-4-yl]benzenesulfonamide |
| InChI | InChI=1S/C12H14N4O4S/c1-19-10-11(14-7-15-12(10)20-2)16-21(17,18)9-5-3-8(13)4-6-9/h3-7H,13H2,1-2H3,(H,14,15,16)/i2D3 |
| InChIKey | PJSFRIWCGOHTNF-BMSJAHLVSA-N |
| SMILES | [2H]C([2H])([2H])OC1=NC=NC(=C1OC)NS(=O)(=O)C2=CC=C(C=C2)N |
| Reference | [1]. Ratcliff A, et al. Therapeutic response of multidrug-resistant Plasmodium falciparum and P. vivax to chloroquine and sulfadoxine-pyrimethamine in southern Papua, Indonesia. Trans R Soc Trop Med Hyg. 2007 Apr;101(4):351-9. [2]. Fey K, et al. Empfindlichkeit bakterieller Krankheitserreger aus dem Respirationstrakt von Pferden gegenüber Trimethoprim, Sulfadoxin, Sulfadimethoxin und Kombinationen dieser Wirkstoffe [Susceptibility of bacterial isolates from the equine respiratory tract to trimethoprim, sulfadoxine, sulfadimethoxine and combinations of these compounds]. Tierarztl Prax. 1995 Apr;23(2):148-54. German. [3]. Baraff LJ. Emergency medicine-important advances in clinical medicine: single-dose treatment of urinary tract infections. West J Med. 1983 Jan;138(1):89-90. [4]. Oguariri RM, et al. Evaluation of the effect of pyrimethamine, an anti-malarial drug, on HIV-1 replication. Virus Res. 2010 Nov;153(2):269-76. [5]. Neerja J, et al. Plasmodium yoelii: activity of azithromycin in combination with pyrimethamine or sulfadoxine against blood and sporozoite induced infections in Swiss mice. Exp Parasitol. 2004 Jul-Aug;107(3-4):120-4. |
