For research use only. Not for therapeutic Use.
Sulfamoxole（Cat No.:R050895）is a sulfonamide antibiotic effective against a range of bacterial infections, particularly those in the urinary and respiratory tracts. It works by inhibiting bacterial folic acid synthesis, an essential pathway for DNA and protein production, thereby preventing bacterial growth. Sulfamoxole is often used in combination with other antibiotics, such as trimethoprim, to enhance its effectiveness and broaden its antimicrobial spectrum. Known for its targeted action and oral bioavailability, Sulfamoxole remains a valuable agent in managing bacterial infections, especially in outpatient settings where convenience and efficacy are essential.
| Catalog Number | R050895 |
| CAS Number | 729-99-7 |
| Synonyms | 4-Amino-N-(4,5-dimethyl-2-oxazolyl)benzenesulfonamide; N1-(4,5-dimethyl-2-oxazolyl)sulfanilamide; 2-(p-Aminobenzolsulfonamido)-4,5-?dimethyloxazole; 2-Sulfanilamido-4,5-dimethyloxazole; Justamil; N1-(4,5-Dimethyl-2-oxazolyl)sulfanilamide; NSC 683535; |
| Molecular Formula | C11H13N3O3S |
| Purity | ≥95% |
| Target | Bacterial |
| Storage | Store at -20°C |
| IUPAC Name | 4-amino-N-(4,5-dimethyl-1,3-oxazol-2-yl)benzenesulfonamide |
| InChI | InChI=1S/C11H13N3O3S/c1-7-8(2)17-11(13-7)14-18(15,16)10-5-3-9(12)4-6-10/h3-6H,12H2,1-2H3,(H,13,14) |
| InChIKey | CYFLXLSBHQBMFT-UHFFFAOYSA-N |
| SMILES | CC1=C(OC(=N1)NS(=O)(=O)C2=CC=C(C=C2)N)C |
| Reference | </br>1:Synthesis, characterization, microbiological evaluation, genotoxicity and synergism tests of new nano silver complexes with sulfamoxole: X-ray diffraction of [Ag2(SMX)2]·DMSO. Velluti F, Mosconi N, Acevedo A, Borthagaray G, Castiglioni J, Faccio R, Back DF, Moyna G, Rizzotto M, Torre MH.J Inorg Biochem. 2014 Dec;141:58-69. doi: 10.1016/j.jinorgbio.2014.08.007. Epub 2014 Aug 19. PMID: 25217718 </br>2:Penicillin, Co-trimoxazole and Sulfamoxole Trimethoparim Combination in the Treatment of Gonorrhoea. Pandhi RK, Bhujwala RA, Thomas J, Bhutani LK.Indian J Dermatol Venereol Leprol. 1983 Mar-Apr;49(2):53-56. PMID: 28176706 Free Article</br>3:In vitro studies with combinations of sulfamoxole and trimethoprim (co-trifamole). Grüneberg RN.Curr Med Res Opin. 1982;8(2):128-33. PMID: 7105824 </br>4:Comparative Evaluation of Ampicillin and Trimethoprim Sulfamoxole Combination in Gonorrhoea. Chendrayudu J, Girgla HS, Singh GM, Vasistha LK, Pandey SS.Indian J Dermatol Venereol Leprol. 1981 May-Jun;47(3):158-161. PMID: 28211439 Free Article</br>5:Plasma levels of trimethoprim and sulfonamide after administration of trimethoprim-sulfamethoxazole and trimethoprim-sulfamoxole. Gupta KC, Desai NK, Paul T, Sheth UK.Int J Clin Pharmacol Ther Toxicol. 1980 Dec;18(12):536-7. PMID: 7228448 </br>6:Non controlled clinical trial of trimethoprim and sulfamoxole (supristol) in bacterial diarrhoea of children. Praharaj SC, Kar AK.Indian J Pediatr. 1979 Nov;46(382):411-6. No abstract available. PMID: 546760 </br>7:[In vitro antibacterial effect of sulfamoxole/trimethoprim and sulfamethoxazole/trimethoprim]. Hingst V, Sonntag HG.Med Welt. 1979 Aug 17;30(33):1199-201. German. No abstract available. PMID: 491915 </br>8:Dispersion of sulfamoxole in tissues of poultry. Banerjee NC, Singh MK, Jha HN, Singh SD.Indian J Physiol Pharmacol. 1977 Jan-Mar;21(1):63-5. PMID: 873593 </br>9:[Efficacy and tolerance of trimethoprim sulfamoxole combination in childhood (author/’s transl)]. Helwig H, Bulla M, Sitzmann W, Schreier K, Loh K, Wodetzky A.Klin Padiatr. 1976 Nov;188(6):518-27. German. PMID: 137345 </br>10:Stevens-Johnson syndrome due to sulfuno (sulfamoxole). Purohit SD, Dhariwal ML.Indian J Chest Dis Allied Sci. 1976 Apr;18(2):105-7. No abstract available. PMID: 1026637 |
