For research use only. Not for therapeutic Use.
Asulfo-SPDB ( Cat No.:I016698 ) is a cleavable ADC linker for the synthesis of antibody-coupled drugs ( ADC ). If you need, please contact us in time, and we will reply to you as soon as possible within 24 hours.
Catalog Number | I016698 |
CAS Number | 1193111-39-5 |
Molecular Formula | C₁₃H₁₄N₂O₇S₃ |
Purity | ≥95% |
Target | ADC Linker |
IUPAC Name | 1-(2,5-dioxopyrrolidin-1-yl)oxy-1-oxo-4-(pyridin-2-yldisulfanyl)butane-2-sulfonic acid |
InChI | InChI=1S/C13H14N2O7S3/c16-11-4-5-12(17)15(11)22-13(18)9(25(19,20)21)6-8-23-24-10-3-1-2-7-14-10/h1-3,7,9H,4-6,8H2,(H,19,20,21) |
InChIKey | FUHCFUVCWLZEDQ-UHFFFAOYSA-N |
SMILES | C1CC(=O)N(C1=O)OC(=O)C(CCSSC2=CC=CC=N2)S(=O)(=O)O |
Reference | [1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337. |