sulfo-SPDB

For research use only. Not for therapeutic Use.

  • CAT Number: I016698
  • CAS Number: 1193111-39-5
  • Molecular Formula: C₁₃H₁₄N₂O₇S₃
  • Molecular Weight: 406.45
  • Purity: ≥95%
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Asulfo-SPDB ( Cat No.:I016698 ) is a cleavable ADC linker for the synthesis of antibody-coupled drugs ( ADC ). If you need, please contact us in time, and we will reply to you as soon as possible within 24 hours.


Catalog Number I016698
CAS Number 1193111-39-5
Molecular Formula C₁₃H₁₄N₂O₇S₃
Purity ≥95%
Target ADC Linker
IUPAC Name 1-(2,5-dioxopyrrolidin-1-yl)oxy-1-oxo-4-(pyridin-2-yldisulfanyl)butane-2-sulfonic acid
InChI InChI=1S/C13H14N2O7S3/c16-11-4-5-12(17)15(11)22-13(18)9(25(19,20)21)6-8-23-24-10-3-1-2-7-14-10/h1-3,7,9H,4-6,8H2,(H,19,20,21)
InChIKey FUHCFUVCWLZEDQ-UHFFFAOYSA-N
SMILES C1CC(=O)N(C1=O)OC(=O)C(CCSSC2=CC=CC=N2)S(=O)(=O)O
Reference

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

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