Sulindac

• CAT Number: A000486
• CAS Number: 38194-50-2
• Molecular Formula: C20H17FO3S
• Molecular Weight: 356.4
• Purity: ≥95%
• Synonyms: Clinoril; Arthrocine; Sulindac sulfoxide; 38194-50-2; Sulindaco
• Target: Immunology/Inflammation
• Solubility: >12.1mg/mL in DMSO
• Storage: -20°C
• InChI: 1S/C20H17FO3S/c1-12-17(9-13-3-6-15(7-4-13)25(2)24)16-8-5-14(21)10-19(16)18(12)11-20(22)23/h3-10H,11H2,1-2H3,(H,22,23)/b17-9-
• InChIKey: MLKXDPUZXIRXEP-MFOYZWKCSA-N
• SMILES: CC1=C(C2=C(C1=CC3=CC=C(C=C3)S(=O)C)C=CC(=C2)F)CC(=O)O

Sulindac is a non-steroidal anti-inflammatory drug of the arylalkanoic acid class. Like other NSAIDs, it is useful in the treatment of acute or chronic inflammatory conditions. Sulindac is a prodrug, derived from sulfinylindene, that is converted in the body to the active NSAID. More specifically, the agent is converted by liver enzymes to a sulfide that is excreted in the bile and then reabsorbed from the intestine.

Reference

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