For research use only. Not for therapeutic Use.
Sulphadimethoxine（Cat No.:A001171）is a long-acting sulfonamide antibiotic widely used in veterinary medicine to treat bacterial infections in animals. Known for its broad-spectrum antimicrobial activity, Sulphadimethoxine effectively targets a range of pathogens by inhibiting folic acid synthesis, which is essential for bacterial growth. Its extended half-life allows for sustained therapeutic levels with less frequent dosing, making it especially valuable in livestock management. In research, Sulphadimethoxine serves as a model for studying antimicrobial resistance and pharmacokinetics, contributing to the development of effective treatment protocols in animal health.
| Catalog Number | A001171 |
| CAS Number | 122-11-2 |
| Synonyms | NA |
| Molecular Formula | C12H14N4O4S |
| Purity | ≥95% |
| Storage | 3 years -20C powder |
| IUPAC Name | 4-amino-N-(2,6-dimethoxypyrimidin-4-yl)benzenesulfonamide |
| InChI | InChI=1S/C12H14N4O4S/c1-19-11-7-10(14-12(15-11)20-2)16-21(17,18)9-5-3-8(13)4-6-9/h3-7H,13H2,1-2H3,(H,14,15,16) |
| InChIKey | ZZORFUFYDOWNEF-UHFFFAOYSA-N |
| SMILES | COC1=NC(=NC(=C1)NS(=O)(=O)C2=CC=C(C=C2)N)OC |
| Reference | </br>1:Comparison of toltrazuril and sulphadimethoxine in the treatment of intestinal coccidiosis in pet rabbits. Redrobe SP, Gakos G, Elliot SC, Saunders R, Martin S, Morgan ER.Vet Rec. 2010 Aug 21;167(8):287-90. doi: 10.1136/vr.c3453. PMID: 20729515 </br>2:Sulphadimethoxine inhibits Phaseolus vulgaris root growth and development of N-fixing nodules. Sartorius M, Riccio A, Cermola M, Casoria P, Patriarca EJ, Taté R.Chemosphere. 2009 Jul;76(3):306-12. doi: 10.1016/j.chemosphere.2009.03.067. Epub 2009 May 6. PMID: 19423149 </br>3:Photodegradation of sulphadimethoxine in water by medium pressure UV lamp. Lester Y, Gozlan I, Avisar D, Mamane H.Water Sci Technol. 2008;58(5):1147-54. doi: 10.2166/wst.2008.668. PMID: 18824816 </br>4:Sulphadimethoxine and Azolla filiculoides Lam.: a model for drug remediation. Forni C, Cascone A, Fiori M, Migliore L.Water Res. 2002 Jul;36(13):3398-403. PMID: 12188140 </br>5:In vitro hepatobiotransformation of sulphadimethoxine in laying hens. Furusawa N.J Vet Med A Physiol Pathol Clin Med. 2001 Apr;48(3):147-52. PMID: 11379388 </br>6:Prevention of pleuropneumonia in pigs by in-feed medication with sulphadimethoxine and sulphamethoxazole in combination with trimethoprim. Mengelers MJ, Kuiper HA, Pijpers A, Verheijden JH, van Miert AS.Vet Q. 2000 Jul;22(3):157-62. PMID: 10952447 </br>7:Simplified determining procedure for routine residue monitoring of sulphamethazine and sulphadimethoxine in milk. Furusawa N.J Chromatogr A. 2000 Nov 17;898(2):185-91. PMID: 11117416 </br>8:Elimination half-lives of sulphadimethoxine and its N4-acetyl metabolite in tissues of laying hens. Furusawa N.Zentralbl Veterinarmed A. 1999 Feb;46(1):59-64. PMID: 10085768 </br>9:Absorbability of sulphamonomethoxine and sulphadimethoxine administered via food of laying hens. Furusawa N.Zentralbl Veterinarmed A. 1998 Jul;45(5):267-9. PMID: 9719757 </br>10:Depletion of dietary sulphamonomethoxine and sulphadimethoxine from various tissues of laying hens. Furusawa N, Mukai T, Ohori H.Br Poult Sci. 1996 May;37(2):435-42. PMID: 8773852 |
