Sultamicillin Tosylate

• CAT Number: R029338
• CAS Number: 83105-70-8
• Molecular Formula: C₃₂H₃₈N₄O₁₂S₃
• Molecular Weight: 766.86
• Purity: ≥95%
• Synonyms: [2S-[2a(2R*,5S*),5a,6b(S*)]]-6-[(Aminophenylacetyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid [[(3,3-Dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-yl)carbonyl]oxy]methyl Ester S,S-Dioxide Mono(4-methylbenzenesulfo
• Target: Bacterial
• Storage: 2-8°C
• IUPAC Name: [(2S,5R)-3,3-dimethyl-4,4,7-trioxo-4λ6-thia-1-azabicyclo[3.2.0]heptane-2-carbonyl]oxymethyl (2S,5R,6R)-6-[[(2R)-2-amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate;4-methylbenzenesulfonic acid
• InChI: InChI=1S/C25H30N4O9S2.C7H8O3S/c1-24(2)17(29-20(32)16(21(29)39-24)27-19(31)15(26)12-8-6-5-7-9-12)22(33)37-11-38-23(34)18-25(3,4)40(35,36)14-10-13(30)28(14)18;1-6-2-4-7(5-3-6)11(8,9)10/h5-9,14-18,21H,10-11,26H2,1-4H3,(H,27,31);2-5H,1H3,(H,8,9,10)/t14-,15-,16-,17+,18+,21-;/m1./s1
• InChIKey: FFCSPKNZHGIDQM-CGAOXQFVSA-N
• SMILES: CC1=CC=C(C=C1)S(=O)(=O)O.CC1(C(N2C(S1)C(C2=O)NC(=O)C(C3=CC=CC=C3)N)C(=O)OCOC(=O)C4C(S(=O)(=O)C5N4C(=O)C5)(C)C)C

Sultamicillin (tosylate)（Cat No.:R029338）is a potent, orally active combination of a β-lactamase inhibitor and an antibiotic. It effectively inhibits β-lactamase enzymes, which are responsible for antibiotic resistance in bacteria, enhancing the antibacterial activity of ampicillin. Sultamicillin (tosylate) is the tosylate salt of the diester formed by combining sulbactam and ampicillin. This unique combination allows it to combat infections caused by β-lactamase-producing bacteria, making it a valuable tool in the treatment of various bacterial infections while overcoming resistance mechanisms.