For research use only. Not for therapeutic Use.
Sultiame is a carbonic anhydrase inhibitor, widely used as an antiepileptic agent.
Sultiame (Sulthiame) is a sulphonamide, and it may exerts antiepileptic activity by producing a modest intracellular acidosis in central neurons via acting as a carbonic anhydrase inhibitor, thereby reducing the frequency of action potentials and epileptiform bursts[1].
| Catalog Number | R055568 |
| CAS Number | 61-56-3 |
| Synonyms | 4-(1,1-dioxothiazinan-2-yl)benzenesulfonamide |
| Molecular Formula | C10H14N2O4S2 |
| Purity | ≥95% |
| InChI | InChI=1S/C10H14N2O4S2/c11-18(15,16)10-5-3-9(4-6-10)12-7-1-2-8-17(12,13)14/h3-6H,1-2,7-8H2,(H2,11,15,16) |
| InChIKey | HMHVCUVYZFYAJI-UHFFFAOYSA-N |
| SMILES | C1CCS(=O)(=O)N(C1)C2=CC=C(C=C2)S(=O)(=O)N |
| Reference | [1]. Milburn-McNulty P, et al. Sulthiame add-on therapy for epilepsy. Cochrane Database Syst Rev. 2015 Oct 28;(10):CD009472. |
