SUN81928

• CAT Number: I036848
• CAS Number: 2377881-92-8
• Molecular Formula: C29H28O8S2
• Molecular Weight: 568.66
• Purity: 98%
• Synonyms: SUN81928; SUN-81928; SUN 81928
• Target: STING
• Solubility: To be determined
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
• IUPAC Name: 4,4'-(propane-1,3-diylbis(6-methoxybenzo[b]thiophene-5,2-diyl))bis(4-oxobutanoic acid)
• InChI: InChI=1S/C29H28O8S2/c1-36-22-14-24-18(12-26(38-24)20(30)6-8-28(32)33)10-16(22)4-3-5-17-11-19-13-27(21(31)7-9-29(34)35)39-25(19)15-23(17)37-2/h10-15H,3-9H2,1-2H3,(H,32,33)(H,34,35)
• InChIKey: SSYYPCWAUQMVJQ-UHFFFAOYSA-N
• SMILES: O=C(O)CCC(C1=CC2=CC(CCCC3=C(OC)C=C4C(C=C(C(CCC(O)=O)=O)S4)=C3)=C(OC)C=C2S1)=O

SUN81928 is a potent and selective inhibitor targeting the STING (Stimulator of Interferon Genes) pathway, crucial in the immune response. By modulating STING activation, SUN81928 plays a vital role in controlling inflammatory responses and enhancing immune system activity. It has potential applications in cancer immunotherapy and autoimmune diseases, where the regulation of STING activity can influence disease progression. SUN81928 is being investigated for its ability to modulate innate immunity and improve therapeutic outcomes in various immunological conditions.