For research use only. Not for therapeutic Use.
Sunepitron is a selective serotonin 5-HT1A autoreceptor agonist, α2-adrenergic antagonist, and dopamine D2 agonist. Anxiolytic, antidepressant.
| Catalog Number | I009649 |
| CAS Number | 148408-65-5 |
| Molecular Formula | C17H23N5O2.HCl |
| Purity | ≥95% |
| IUPAC Name | 1-[[(7S,9aS)-2-pyrimidin-2-yl-1,3,4,6,7,8,9,9a-octahydropyrido[1,2-a]pyrazin-7-yl]methyl]pyrrolidine-2,5-dione;hydrochloride |
| InChI | InChI=1S/C17H23N5O2.ClH/c23-15-4-5-16(24)22(15)11-13-2-3-14-12-21(9-8-20(14)10-13)17-18-6-1-7-19-17;/h1,6-7,13-14H,2-5,8-12H2;1H/t13-,14-;/m0./s1 |
| SMILES | C1C[C@H]2CN(CCN2C[C@H]1CN3C(=O)CCC3=O)C4=NC=CC=N4.Cl |
| Reference | S.T. Colgan et al. Assay and purity evaluation of sunepitron hydrochloride by reversed-phase liquid chromatography using a reference standard composite. J Pharm Biomed Anal. 1998 Nov;18(3):429-40.
J. Silvestre et al. Sunepitron Hydrochloride. Drugs Fut. 1998; 23(2):161-165.
C. Prakash et al. Metabolism and excretion of a novel antianxiety drug candidate, CP-93,393, in Long Evans rats. Differentiation of regioisomeric glucuronides by LC/MS/MS. Drug Metab Dispos. 1997 Nov;25(11):1288-97.
C. Prakash et al. Metabolism and excretion of a new anxiolytic drug candidate, CP-93, 393, in healthy male volunteers. Drug Metab Dispos. 1998 May;26(5):448-56. |
