Sunifiram

• CAT Number: I003119
• CAS Number: 314728-85-3
• Molecular Formula: C14H18N2O2
• Molecular Weight: 246.3
• Purity: ≥95%
• Target: Neuronal Signaling
• Solubility: DMSO: ≥ 2.6 mg/mL
• Storage: 3 years -20C powder

Sunifiram (CAT: I003119), also known as DM-235, is a compound belonging to the ampakine class of drugs. It has been found to exhibit nootropic effects in animal studies, demonstrating significantly higher potency compared to piracetam, another well-known nootropic agent. Nootropics are substances that are believed to enhance cognitive function, including memory, learning, and focus. Sunifiram is thought to exert its effects by modulating AMPA receptor activity, which plays a role in synaptic plasticity and memory formation.

Reference

[1]. Galeotti N, et al. AMPA-receptor activation is involved in the antiamnesic effect of DM 232 (unifiram) and DM 235 (sunifiram). Naunyn Schmiedebergs Arch Pharmacol. 2003 Dec;368(6):538-45.
[2]. Moriguchi S, et al. Novel nootropic drug sunifiram enhances hippocampal synaptic efficacy via glycine-binding site of N-methyl-D-aspartate receptor. Hippocampus. 2013 Jun 3.
[3]. Moriguchi S, et al. Novel nootropic drug sunifiram improves cognitive deficits via CaM kinase II and protein kinase C activation in olfactory bulbectomized mice. Behav Brain Res. 2013 Apr 1;242:150-7.