Sunitinib N-Oxide-d10

• CAT Number: R021820
• CAS Number: NA
• Molecular Formula: C₂₂H₁₇D₁₀FN₄O₃
• Molecular Weight: 424.53
• Purity: ≥95%
• Synonyms: N-[2-(Diethyloxidoamino)ethyl]-5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide-d10; 5-(5-Fluoro-2-oxo-1,2-dihydroindol-(3Z)-ylidenemethyl)-2,4-dimethyl-1H-pyrrole-3-carboxylic acid (2-diethyl-N-oxoa
• Storage: -20°C
• IUPAC Name: 1,1,2,2,2-pentadeuterio-N-[2-[[5-[(Z)-(5-fluoro-2-oxo-1H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carbonyl]amino]ethyl]-N-(1,1,2,2,2-pentadeuterioethyl)ethanamine oxide
• InChI: InChI=1S/C22H27FN4O3/c1-5-27(30,6-2)10-9-24-22(29)20-13(3)19(25-14(20)4)12-17-16-11-15(23)7-8-18(16)26-21(17)28/h7-8,11-12,25H,5-6,9-10H2,1-4H3,(H,24,29)(H,26,28)/b17-12-/i1D3,2D3,5D2,6D2
• InChIKey: DNCVCKYIYMUMFC-BLSNYXODSA-N
• SMILES: [2H]C([2H])([2H])C([2H])([2H])[N+](CCNC(=O)C1=C(NC(=C1C)/C=C\2/C3=C(C=CC(=C3)F)NC2=O)C)(C([2H])([2H])C([2H])([2H])[2H])[O-]

Sunitinib N-Oxide-d10 is a deuterated form of Sunitinib N-Oxide, featuring ten deuterium atoms. This compound is used in pharmaceutical research to study the metabolism, pharmacokinetics, and interactions of sunitinib, an anti-cancer drug. The deuterium labeling enhances the precision of analytical techniques such as NMR and mass spectrometry, allowing for detailed tracking of the compound’s behavior in biological systems. Sunitinib N-Oxide-d10 aids in understanding the metabolic pathways and stability of sunitinib, optimizing drug formulations, and improving therapeutic strategies for cancer treatment by providing accurate data on drug dynamics and interactions.