For research use only. Not for therapeutic Use.
Sunobinop(CAT: I036851) (also known as IMB-115 or S-556935) is an investigational small-molecule drug that functions as a dual antagonist of the neuropeptide Y (NPY) Y1 receptor and the neurokinin 1 (NK1) receptor. By simultaneously blocking these receptors, Sunobinop modulates pathways involved in pain perception, anxiety, and stress responses. This dual mechanism offers therapeutic potential for treating conditions such as chronic pain, migraine, anxiety disorders, and possibly depression. Sunobinop is currently under investigation for its ability to provide more effective relief by targeting both neuropeptide signaling and stress-related pathways in neurological and psychiatric disorders.
| CAS Number | 1126793-40-5 |
| Synonyms | Sunobinop; Sunobinopum; |
| Molecular Formula | C26H33N3O3 |
| Purity | 98% |
| Solubility | Soluble in DMSO |
| Appearance | Solid powder |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| IUPAC Name | 4-[(1R,5S)-9-[(1S,5S)-3-bicyclo[3.3.1]nonanyl]-9-azabicyclo[3.3.1]nonan-3-yl]-3-oxoquinoxaline-2-carboxylic acid |
| InChI | InChI=1S/C26H33N3O3/c30-25-24(26(31)32)27-22-9-1-2-10-23(22)29(25)21-14-18-7-4-8-19(15-21)28(18)20-12-16-5-3-6-17(11-16)13-20/h1-2,9-10,16-21H,3-8,11-15H2,(H,31,32)/t16-,17-,18+,19+/m1/s1 |
| InChIKey | COTYYZPYDJKKIS-YRXWBPOGSA-N |
| SMILES | O=C(C(C(O)=O)=N1)N(C2C[C@@H](N3C4C[C@@H](C5)CCC[C@H]5C4)CCC[C@H]3C2)C6=C1C=CC=C6 |
