Suvorexant-d6

• CAT Number: R014420
• CAS Number: NA
• Molecular Formula: C₂₃H₁₇D₆ClN₆O₂
• Molecular Weight: 456.96
• Purity: ≥95%
• Synonyms: [(7R)-4-(5-Chloro-2-benzoxazolyl)hexahydro-7-methyl-1H-1,4-diazepin-1-yl][5-methyl-d3-2-(2H-1,2,3-triazol-2-yl)phenyl-d3]-methanone;?5-Chloro-2-[(5R)-5-methyl-4-[5-methyl-d3-2-(2H-1,2,3-triazol-2-yl)benzoyl-d3]-1,4-diazepan-1-yl]-1,3-benzoxazole; MK
• Storage: -20°C
• IUPAC Name: [(7R)-4-(5-chloro-1,3-benzoxazol-2-yl)-7-methyl-1,4-diazepan-1-yl]-[2,4,5-trideuterio-6-(triazol-2-yl)-3-(trideuteriomethyl)phenyl]methanone
• InChI: InChI=1S/C23H23ClN6O2/c1-15-3-5-20(30-25-8-9-26-30)18(13-15)22(31)29-12-11-28(10-7-16(29)2)23-27-19-14-17(24)4-6-21(19)32-23/h3-6,8-9,13-14,16H,7,10-12H2,1-2H3/t16-/m1/s1/i1D3,3D,5D,13D
• InChIKey: JYTNQNCOQXFQPK-WRWCNMDHSA-N
• SMILES: [2H]C1=C(C(=C(C(=C1C([2H])([2H])[2H])[2H])C(=O)N2CCN(CC[C@H]2C)C3=NC4=C(O3)C=CC(=C4)Cl)N5N=CC=N5)[2H]

Suvorexant-d6 is a deuterated form of Suvorexant, a dual orexin receptor antagonist used for the treatment of insomnia. The deuterium labeling in Suvorexant-d6 facilitates precise pharmacokinetic and metabolic studies by enabling accurate tracing and quantification in biological systems. In pharmaceutical research, it helps elucidate the drug’s absorption, distribution, metabolism, and excretion, contributing to a better understanding of its therapeutic efficacy and safety profile. Additionally, in organic chemistry, Suvorexant-d6 is used to study reaction mechanisms and optimize synthetic methodologies, supporting the development of advanced analytical techniques for drug research and development.