SW2_152F

• CAT Number: I043610
• Molecular Formula: C45H62Cl3N7O8
• Molecular Weight: 935.37
• Purity: ≥95%
• Synonyms: 3,5-dichloro-N-[(2S)-3-(3-chloro-4-hydroxyphenyl)-1-[[(1S)-1-cyclopentyl-2-[[(2S,3S)-1-[[(2S)-6-(diethylamino)-1-[[(2S)-1-(ethynylamino)-3-hydroxy-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1-oxopropan-2-yl]benzamide
• IUPAC Name: 3,5-dichloro-N-[(2S)-3-(3-chloro-4-hydroxyphenyl)-1-[[(1S)-1-cyclopentyl-2-[[(2S,3S)-1-[[(2S)-6-(diethylamino)-1-[[(2S)-3-hydroxy-1-oxo-1-(prop-2-ynylamino)propan-2-yl]amino]-1-oxohexan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1-oxopropan-2-yl]benzamide
• InChI: InChI=1S/C45H62Cl3N7O8/c1-6-19-49-41(59)36(26-56)52-42(60)34(16-12-13-20-55(8-3)9-4)50-44(62)38(27(5)7-2)53-45(63)39(29-14-10-11-15-29)54-43(61)35(22-28-17-18-37(57)33(48)21-28)51-40(58)30-23-31(46)25-32(47)24-30/h1,17-18,21,23-25,27,29,34-36,38-39,56-57H,7-16,19-20,22,26H2,2-5H3,(H,49,59)(H,50,62)(H,51,58)(H,52,60)(H,53,63)(H,54,61)/t27-,34-,35-,36-,38-,39-/m0/s1
• InChIKey: AIAWLHFAIHGOGP-NLQBKIGRSA-N
• SMILES: CC[C@H](C)[C@@H](C(=O)N[C@@H](CCCCN(CC)CC)C(=O)N[C@@H](CO)C(=O)NCC#C)NC(=O)[C@H](C1CCCC1)NC(=O)[C@H](CC2=CC(=C(C=C2)O)Cl)NC(=O)C3=CC(=CC(=C3)Cl)Cl

SW2_152F（Cat No.:I043610）is a selective inhibitor of the Wnt/β-catenin signaling pathway, which is crucial for regulating cell proliferation, differentiation, and survival. The Wnt/β-catenin pathway is frequently dysregulated in various cancers, leading to uncontrolled cell growth and metastasis. By inhibiting SW2_152F, this compound aims to suppress abnormal activation of this pathway, offering potential therapeutic benefits in treating cancers driven by Wnt/β-catenin signaling. SW2_152F’s ability to selectively target this pathway makes it a promising candidate for precision oncology, particularly in cancers where this signaling is a major driver of disease progression.