For research use only. Not for therapeutic Use.
Inhibitor of plasminogen activator inhibitor-1 (PAI-1)
| Catalog Number | I047564 |
| CAS Number | 1202075-60-2 |
| Molecular Formula | C25H18NNaO4 |
| Purity | ≥95% |
| IUPAC Name | sodium;2-[3-[(Z)-(5-oxo-3,4-diphenylpyrrol-2-ylidene)methyl]phenoxy]acetate |
| InChI | InChI=1S/C25H19NO4.Na/c27-22(28)16-30-20-13-7-8-17(14-20)15-21-23(18-9-3-1-4-10-18)24(25(29)26-21)19-11-5-2-6-12-19;/h1-15H,16H2,(H,26,29)(H,27,28);/q;+1/p-1/b21-15-; |
| SMILES | C1=CC=C(C=C1)C\2=C(C(=O)N/C2=C\C3=CC(=CC=C3)OCC(=O)[O-])C4=CC=CC=C4.[Na+] |
| Reference | H Miyazaki et al. Synthesis and Evaluation of Pyrrolin-2-one Compounds, a Series of Plasminogen Activator Inhibitor-1 Inhibitors. Chem. Pharm. Bull. 2009, 57(9), 979-985.
H Miyazaki et al. Evaluation of pyrrolin-2-one derivatives synthesized by a new practical method as inhibitors of plasminogen activator inhibitor-1 (PAI-1). Bioorg. Med. Chem. Lett. 2010, 20(2), 546-548. |
