For research use only. Not for therapeutic Use.
T-3764518 is a novel and potent stearoyl coenzyme A desaturase (SCD) inhibitor with an IC50 of 4.7 nM.
| Catalog Number | I019554 |
| CAS Number | 1809151-56-1 |
| Synonyms | [5-[6-[4-(trifluoromethyl)-4-[4-(trifluoromethyl)phenyl]piperidin-1-yl]pyridazin-3-yl]-1,3,4-oxadiazol-2-yl]methanol |
| Molecular Formula | C20H17F6N5O2 |
| Purity | ≥95% |
| InChI | InChI=1S/C20H17F6N5O2/c21-19(22,23)13-3-1-12(2-4-13)18(20(24,25)26)7-9-31(10-8-18)15-6-5-14(27-28-15)17-30-29-16(11-32)33-17/h1-6,32H,7-11H2 |
| InChIKey | TVGUBMHUHTULAD-UHFFFAOYSA-N |
| SMILES | C1CN(CCC1(C2=CC=C(C=C2)C(F)(F)F)C(F)(F)F)C3=NN=C(C=C3)C4=NN=C(O4)CO |
| Reference | [1]. Imamura K, et al. Discovery of Novel and Potent Stearoyl Coenzyme A Desaturase 1 (SCD1) Inhibitors as Anticancer Agents. Bioorg Med Chem. 2017 Jul 15;25(14):3768-3779. |
