t-Boc-aminooxy-PEG3-propargyl

• CAT Number: I014714
• CAS Number: 1951439-46-5
• Molecular Formula: C14H25NO6
• Molecular Weight: 303.36
• Purity: ≥95%
• Synonyms: t-Boc-aminooxy-PEG3-propargyl;tert-butyl (2-(2-(2-(prop-2-yn-1-yloxy)ethoxy)ethoxy)ethoxy)carbamate
• Solubility: Soluble in DMSO
• IUPAC Name: tert-butyl N-[2-[2-(2-prop-2-ynoxyethoxy)ethoxy]ethoxy]carbamate
• InChI: InChI=1S/C14H25NO6/c1-5-6-17-7-8-18-9-10-19-11-12-20-15-13(16)21-14(2,3)4/h1H,6-12H2,2-4H3,(H,15,16)
• InChIKey: VMOMFXUHEJCHQS-UHFFFAOYSA-N
• SMILES: O=C(OC(C)(C)C)NOCCOCCOCCOCC#C

t-Boc-aminooxy-PEG3-propargyl(CAT: I014714) is a versatile polyethylene glycol (PEG) derivative designed for bioconjugation applications. It features a tert-butyloxycarbonyl (t-Boc)-protected aminooxy group, a PEG3 spacer for enhanced solubility, and a terminal propargyl group for Click Chemistry reactions. The aminooxy group can react with carbonyl groups, such as aldehydes and ketones, to form stable oxime bonds after deprotection of the t-Boc group. The propargyl group enables copper-catalyzed azide-alkyne cycloaddition (CuAAC) for conjugation with azide-functionalized molecules. t-Boc-aminooxy-PEG3-propargyl is widely used in bioconjugation, surface modification, and the development of functional biomaterials for research in drug delivery, diagnostics, and molecular imaging.