For research use only. Not for therapeutic Use.
T0070907-d4 (Cat No.: I040120) is a deuterated analog of T0070907, a selective inhibitor of peroxisome proliferator-activated receptor gamma (PPAR-γ) coactivator-1 (PGC-1). The deuteration (replacement of hydrogen with deuterium) enhances the compound’s stability and provides useful advantages in pharmacokinetic studies. T0070907-d4 is primarily used in research to explore the role of PGC-1 in metabolic diseases, obesity, and cardiovascular conditions. By inhibiting PGC-1, it helps to modulate metabolic pathways and may offer insights into therapeutic strategies for related disorders.
| Synonyms | 2-chloro-5-nitro-N-(2,3,5,6-tetradeuteriopyridin-4-yl)benzamide |
| Molecular Formula | C12H4D4ClN3O3 |
| Purity | ≥95% |
| InChI | InChI=1S/C12H8ClN3O3/c13-11-2-1-9(16(18)19)7-10(11)12(17)15-8-3-5-14-6-4-8/h1-7H,(H,14,15,17)/i3D,4D,5D,6D |
| InChIKey | FRPJSHKMZHWJBE-LNFUJOGGSA-N |
| SMILES | C1=CC(=C(C=C1[N+](=O)[O-])C(=O)NC2=CC=NC=C2)Cl |
| Reference | [1]. An Z, et al. T0070907 inhibits repair of radiation-induced DNA damage by targeting RAD51. Toxicol In Vitro. 2016 Dec;37:1-8 |
