For research use only. Not for therapeutic Use.
Proliferating cell nuclear antigen (PCNA) inhibitor; inhibits PCNA/PIP-box peptide interaction (IC<sub>50</sub> ~1 <span class=/’symbol/’>μ</span>M). Causes DNA replication stress by stalling DNA replication forks. Inhibits PCNA interaction with DNA polymerase <span class=/’symbol/’>δ</span> and arrests cell growth in S-phase. Suppresses cancer cell growth.
| Catalog Number | I011012 |
| CAS Number | 1380782-27-3 |
| Synonyms | (βS)-β-Amino-4-(4-hydroxyphenoxy)-3,5-diiodobenzenpropanol |
| Molecular Formula | C15H15I2NO3 |
| Purity | ≥95% |
| Target | DNA/RNA Synthesis |
| Solubility | Soluble to 100 mM in DMSO |
| Storage | Store at -20C |
