For research use only. Not for therapeutic Use.
T807（Cat No.:I013638） is a novel positron emission tomography (PET) tracer designed to target tau protein, a key hallmark of neurodegenerative diseases such as Alzheimer’s disease. It binds specifically to abnormal tau aggregates in the brain, allowing for non-invasive imaging and detection of tau pathology. T807 PET imaging provides valuable information about the distribution and progression of tau pathology in living subjects, aiding in early diagnosis and monitoring of neurodegenerative disorders. The development of tau-specific PET tracers like T807 has significantly advanced our understanding and diagnosis of tau-related diseases.
| Catalog Number | I013638 |
| CAS Number | 1415379-56-4 |
| Molecular Formula | C₁₆H₁₀FN₃ |
| Purity | ≥95% |
| Target | Tau Protein |
| Solubility | DMSO: ≥16.6 mg/mL |
| Storage | Store at -20°C |
| IUPAC Name | 7-(6-fluoropyridin-3-yl)-5H-pyrido[4,3-b]indole |
| InChI | InChI=1S/C16H10FN3/c17-16-4-2-11(8-19-16)10-1-3-12-13-9-18-6-5-14(13)20-15(12)7-10/h1-9,20H |
| InChIKey | GETAAWDSFUCLBS-UHFFFAOYSA-N |
| SMILES | C1=CC2=C(C=C1C3=CN=C(C=C3)F)NC4=C2C=NC=C4 |
| Reference | [1]. Xia CF, et al. [(18)F]T807, a novel tau positron emission tomography imaging agent for Alzheimer//’s disease. Alzheimers Dement. 2013 Nov;9(6):666-76. <br>[2]. Marquié M, et al. Validating novel tau positron emission tomography tracer [F-18]-AV-1451 (T807) on postmortem brain tissue. Ann Neurol. 2015 Nov;78(5):787-800. |
