For research use only. Not for therapeutic Use.
TAE-1 is a potent inhibitor of AChE and BuChE. TAE-1 also inhibits Aβ fibril formation and aggregation. TAE-1 can be used for the researches of Alzheimer’s disease[1].
| Catalog Number | I011441 |
| CAS Number | 1414469-59-2 |
| Synonyms | 2-[4-[[4,6-bis[4-[2-(trimethylazaniumyl)ethoxycarbonyl]phenoxy]-1,3,5-triazin-2-yl]oxy]benzoyl]oxyethyl-trimethylazanium;triiodide |
| Molecular Formula | C39H51I3N6O9 |
| Purity | ≥95% |
| InChI | InChI=1S/C39H51N6O9.3HI/c1-43(2,3)22-25-49-34(46)28-10-16-31(17-11-28)52-37-40-38(53-32-18-12-29(13-19-32)35(47)50-26-23-44(4,5)6)42-39(41-37)54-33-20-14-30(15-21-33)36(48)51-27-24-45(7,8)9;;;/h10-21H,22-27H2,1-9H3;3*1H/q+3;;;/p-3 |
| InChIKey | SGOMELGTKOLYEZ-UHFFFAOYSA-K |
| SMILES | C[N+](C)(C)CCOC(=O)C1=CC=C(C=C1)OC2=NC(=NC(=N2)OC3=CC=C(C=C3)C(=O)OCC[N+](C)(C)C)OC4=CC=C(C=C4)C(=O)OCC[N+](C)(C)C.[I-].[I-].[I-] |
| Reference | [1]. Veloso AJ, et al. Biological activity of sym-triazines with acetylcholine-like substitutions as multitarget modulators of Alzheimer’s disease. ACS Chem Neurosci. 2013 Jun 19;4(6):924-9. |
