For research use only. Not for therapeutic Use.
Tafenoquine（Cat No.:M004199）is an antimalarial drug used for the prevention and treatment of malaria, including both the blood and liver stages caused by Plasmodium vivax and Plasmodium falciparum. As a synthetic analogue of primaquine, Tafenoquine works by disrupting the parasite’s mitochondrial function, leading to its death. Its long half-life allows for single-dose treatment of relapsing P. vivax malaria and once-weekly dosing for malaria prophylaxis. Tafenoquine is effective in preventing relapses and offers a convenient option for malaria management, especially in regions where the disease is endemic and recurrent.
| Catalog Number | M004199 |
| CAS Number | 106635-80-7 |
| Molecular Formula | C24H28F3N3O3 |
| Purity | 98% |
| Target | CYC1-MT-CYB |
| Target Protein | P08574 |
| Appearance | Solid |
| Storage | Dry, dark and at 2 - 8 °C for six months or -20°C for two years. |
| IUPAC Name | 4-N-[2,6-dimethoxy-4-methyl-5-[3-(trifluoromethyl)phenoxy]quinolin-8-yl]pentane-1,4-diamine |
| InChI | InChI=1S/C24H28F3N3O3/c1-14-11-20(32-4)30-22-18(29-15(2)7-6-10-28)13-19(31-3)23(21(14)22)33-17-9-5-8-16(12-17)24(25,26)27/h5,8-9,11-13,15,29H,6-7,10,28H2,1-4H3 |
| InChIKey | LBHLFPGPEGDCJG-UHFFFAOYSA-N |
| SMILES | CC1=CC(=NC2=C1C(=C(C=C2NC(C)CCCN)OC)OC3=CC=CC(=C3)C(F)(F)F)OC |
