TAK1-IN-4

• CAT Number: I043477
• CAS Number: 1570374-32-1
• Molecular Formula: C18H17N3O3
• Molecular Weight: 323.35
• Purity: ≥95%
• Synonyms: 3-[(1-propylbenzimidazol-2-yl)carbamoyl]benzoic acid
• InChI: InChI=1S/C18H17N3O3/c1-2-10-21-15-9-4-3-8-14(15)19-18(21)20-16(22)12-6-5-7-13(11-12)17(23)24/h3-9,11H,2,10H2,1H3,(H,23,24)(H,19,20,22)
• InChIKey: OWYWEJQTFNMMSF-UHFFFAOYSA-N
• SMILES: CCCN1C2=CC=CC=C2N=C1NC(=O)C3=CC(=CC=C3)C(=O)O

TAK1-IN-4（Cat No.:I043477）is a selective inhibitor of TGF-beta-activated kinase 1 (TAK1), a pivotal enzyme involved in various inflammatory and fibrotic diseases. By targeting TAK1, TAK1-IN-4 modulates key signaling pathways such as NF-kB and MAPK, which are crucial in inflammation, immune responses, and tissue fibrosis. This compound is being explored for its potential in treating conditions like autoimmune diseases, fibrosis, and cancer. Its high specificity for TAK1 makes it a promising candidate for precision therapies aimed at reducing unwanted inflammatory responses and promoting tissue repair without broad immune suppression.