For research use only. Not for therapeutic Use.
TAM470（Cat No.:I042760）is a small molecule compound that acts as a potent inhibitor of certain kinases involved in regulating cell growth, survival, and proliferation. It is particularly studied for its effects on cancer cells, where dysregulated kinase activity often drives tumorigenesis. By inhibiting these kinases, TAM470 disrupts critical signaling pathways that contribute to cancer cell survival and resistance to treatments. Researchers are exploring TAM470 as a potential therapeutic agent for various cancers, particularly those with specific kinase-driven mutations, aiming to improve the efficacy of targeted cancer therapies and reduce tumor progression.
| CAS Number | 1802498-63-0 |
| Synonyms | N-[(2R,4S)-5-hydrazinyl-1-(4-hydroxyphenyl)-4-methyl-5-oxopentan-2-yl]-2-[(1R,3R)-4-methyl-3-[[(2S,3S)-3-methyl-2-[[(2R)-1-methylpiperidine-2-carbonyl]amino]pentanoyl]-propylamino]-1-propoxypentyl]-1,3-thiazole-4-carboxamide |
| Molecular Formula | C41H67N7O6S |
| Purity | ≥95% |
| IUPAC Name | N-[(2R,4S)-5-hydrazinyl-1-(4-hydroxyphenyl)-4-methyl-5-oxopentan-2-yl]-2-[(1R,3R)-4-methyl-3-[[(2S,3S)-3-methyl-2-[[(2R)-1-methylpiperidine-2-carbonyl]amino]pentanoyl]-propylamino]-1-propoxypentyl]-1,3-thiazole-4-carboxamide |
| InChI | InChI=1S/C41H67N7O6S/c1-9-19-48(41(53)36(27(6)11-3)45-39(52)33-14-12-13-20-47(33)8)34(26(4)5)24-35(54-21-10-2)40-44-32(25-55-40)38(51)43-30(22-28(7)37(50)46-42)23-29-15-17-31(49)18-16-29/h15-18,25-28,30,33-36,49H,9-14,19-24,42H2,1-8H3,(H,43,51)(H,45,52)(H,46,50)/t27-,28-,30+,33+,34+,35+,36-/m0/s1 |
| InChIKey | WZNRAPVOSYSOAK-WPIAVMABSA-N |
| SMILES | CCCN([C@H](C[C@H](C1=NC(=CS1)C(=O)N[C@@H](CC2=CC=C(C=C2)O)C[C@H](C)C(=O)NN)OCCC)C(C)C)C(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H]3CCCCN3C |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
