Tamapin TFA

• CAT Number: I040809
• Molecular Formula: C146H238N44O41S6.xC2HF3O2
• Molecular Weight: 3458.11 (free base)
• Purity: ≥95%

Tamapin TFA (Cat No.: I040809) is a selective peptide inhibitor of small-conductance calcium-activated potassium (SK) channels, particularly SK2 subtypes. Derived from the venom of the Indian red scorpion (Mesobuthus tamulus), Tamapin is valuable in neuroscience research for probing SK channel function in neuronal excitability, synaptic transmission, and memory formation. Its high affinity and subtype selectivity make it a powerful tool for distinguishing SK2-mediated processes from other SK channel activities. Tamapin TFA is supplied as a trifluoroacetate salt. For research use only.

Reference

[1]. Pedarzani P, et al. Tamapin, a venom peptide from the Indian red scorpion (Mesobuthus tamulus) that targets small conductance Ca2+-activated K+ channels and afterhyperpolarization currents in central neurons. J Biol Chem. 2002 Nov 29;277(48):46101-9.
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