For research use only. Not for therapeutic Use.
Tamoxifen（Cat No.:A001101）is a selective estrogen receptor modulator (SERM) commonly used in the treatment and prevention of hormone-receptor-positive breast cancer. It works by binding to estrogen receptors on cancer cells, blocking estrogen from binding and stimulating the growth of tumors. While it has antitumor effects in breast tissue, it can act as an estrogen agonist in other tissues, such as the uterus and bone. Tamoxifen has been shown to reduce the recurrence of breast cancer and improve survival rates. It is often prescribed for both premenopausal and postmenopausal women and has proven effectiveness in reducing the risk of breast cancer.
| Catalog Number | A001101 |
| CAS Number | 10540-29-1 |
| Synonyms | ICI 46474 |
| Molecular Formula | C26H29NO |
| Purity | ≥95% |
| Target | Metabolic Enzyme/Protease |
| Storage | 3 years -20C powder |
| IUPAC Name | 2-[4-[(Z)-1,2-diphenylbut-1-enyl]phenoxy]-N,N-dimethylethanamine |
| InChI | InChI=1S/C26H29NO/c1-4-25(21-11-7-5-8-12-21)26(22-13-9-6-10-14-22)23-15-17-24(18-16-23)28-20-19-27(2)3/h5-18H,4,19-20H2,1-3H3/b26-25- |
| InChIKey | NKANXQFJJICGDU-QPLCGJKRSA-N |
| SMILES | CC/C(=C(\C1=CC=CC=C1)/C2=CC=C(C=C2)OCCN(C)C)/C3=CC=CC=C3 |
| Reference | Clemons, M., S. Danson, and A. Howell. /Tamoxifen (‘Nolvadex’): A Review./ Cancer Treatment Reviews 28.4 (2002): 165-80. Web.</span></p> |
