For research use only. Not for therapeutic Use.
Targocil-II (Cat No.: I040068) is a potent antibacterial compound targeting cell wall biosynthesis, making it valuable for infectious disease research and antibiotic development. It specifically inhibits wall teichoic acid (WTA) synthesis, a crucial component of Gram-positive bacterial cell walls, leading to bacterial growth inhibition and cell death. With high selectivity and efficacy, Targocil-II is ideal for in vitro and in vivo studies, supporting the discovery of novel antimicrobial agents to combat antibiotic-resistant bacterial infections and advance infectious disease therapeutics.
| CAS Number | 955918-74-8 |
| Synonyms | (2S)-1-[2-[3-(4-chlorophenyl)-5,9-dimethyl-7-oxofuro[3,2-g]chromen-6-yl]acetyl]pyrrolidine-2-carboxylic acid |
| Molecular Formula | C26H22ClNO6 |
| Purity | ≥95% |
| InChI | InChI=1S/C26H22ClNO6/c1-13-17-10-19-20(15-5-7-16(27)8-6-15)12-33-23(19)14(2)24(17)34-26(32)18(13)11-22(29)28-9-3-4-21(28)25(30)31/h5-8,10,12,21H,3-4,9,11H2,1-2H3,(H,30,31)/t21-/m0/s1 |
| InChIKey | AKQCCBGXRNNPLS-NRFANRHFSA-N |
| SMILES | CC1=C(C(=O)OC2=C(C3=C(C=C12)C(=CO3)C4=CC=C(C=C4)Cl)C)CC(=O)N5CCCC5C(=O)O |
| Reference | [1]. Matano LM, et al. Antibiotic That Inhibits the ATPase Activity of an ATP-Binding Cassette Transporter by Binding to a Remote Extracellular Site. J Am Chem Soc. 2017 Aug 9;139(31):10597-10600. |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
