For research use only. Not for therapeutic Use.
TAS1553（Cat No.:I043309）is a novel small-molecule inhibitor that targets the 5-HT3 receptor, a subtype of serotonin receptor involved in neurotransmission, particularly in the central nervous system and gastrointestinal tract. By modulating the 5-HT3 receptor, TAS1553 aims to treat disorders related to serotonin imbalances, such as nausea, vomiting, and gastrointestinal dysfunction. It has shown potential in preclinical studies for managing chemotherapy-induced nausea and irritable bowel syndrome (IBS). Ongoing research is focused on assessing its safety, efficacy, and potential for clinical use in treating serotonin-related disorders and enhancing patient outcomes in gastrointestinal conditions.
| CAS Number | 2166023-31-8 |
| Synonyms | 5-chloro-2-[[(1S,2R)-2-(6-fluoro-2,3-dimethylphenyl)-1-(2-oxo-3H-1,3,4-oxadiazol-5-yl)propyl]sulfamoyl]benzamide |
| Molecular Formula | C20H20ClFN4O5S |
| Purity | ≥95% |
| IUPAC Name | 5-chloro-2-[[(1S,2R)-2-(6-fluoro-2,3-dimethylphenyl)-1-(2-oxo-3H-1,3,4-oxadiazol-5-yl)propyl]sulfamoyl]benzamide |
| InChI | InChI=1S/C20H20ClFN4O5S/c1-9-4-6-14(22)16(10(9)2)11(3)17(19-24-25-20(28)31-19)26-32(29,30)15-7-5-12(21)8-13(15)18(23)27/h4-8,11,17,26H,1-3H3,(H2,23,27)(H,25,28)/t11-,17+/m1/s1 |
| InChIKey | DUYRWEBTZNUILI-DIFFPNOSSA-N |
| SMILES | CC1=C(C(=C(C=C1)F)[C@@H](C)[C@@H](C2=NNC(=O)O2)NS(=O)(=O)C3=C(C=C(C=C3)Cl)C(=O)N)C |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
