Tat-peptide 190-208 TFA

• CAT Number: I041206
• Molecular Formula: C142H214N40O57.C2HF3O2
• Molecular Weight: 3507.47
• Purity: ≥95%

Tat-peptide 190-208 TFA is a cell-permeable and Tat-labeled fusion peptide, corresponding to residues 190-208 of rat G3BP1. Tat sequence from HIV, is placed at the least conserved end of the sequence, for cell permeability. Tat-peptide 190-208 TFA increases axon growth and increases the number of neurites per neuron. Tat-peptide 190-208 TFA likely exhibits an axon intrinsic mechanism. Tat-peptide 190-208 TFA can be used for ischemic protection during endovascular repair for intracranial aneurysms[1].
Tat-peptide 190-208 TFA (10 μM, 20 μM; 24 h) increases axon length in dissociated DRG cultures with 10 μM, as well as in iMotor neurons with 20 μM[1].
Tat-peptide 190-208 TFA (10 μM; 3 d) increases the overall number of neurites extended from each neuron[1].

Reference

[1]. Sahoo PK, et al. Axonal G3BP1 stress granule protein limits axonal mRNA translation and nerve regeneration.
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