Tau ASO-12 (murine) (sodium)

• CAT Number: I041016
• Molecular Weight: 7619.00
• Purity: ≥95%

Tau ASO-12 (murine) (sodium) (Cat No.: I041016) is an antisense oligonucleotide (ASO) designed to selectively bind and reduce Tau mRNA expression in murine models. By targeting Tau, a microtubule-associated protein implicated in neurodegenerative diseases such as Alzheimer’s and frontotemporal dementia, this ASO facilitates the study of Tau-related pathology and therapeutic interventions. The sodium salt form improves stability and solubility for in vivo and in vitro applications. Tau ASO-12 is a valuable research tool for studying Tau suppression. For research use only.

Reference

[1]. DeVos SL, Miller RL, Schoch KM, et al. Tau reduction prevents neuronal loss and reverses pathological tau deposition and seeding in mice with tauopathy. Sci Transl Med. 2017;9(374):eaag0481.
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