Tauro-β-muricholic Acid (sodium salt)

• CAT Number: R066738
• CAS Number: 145022-92-0
• Molecular Formula: C26H44NO7S • Na
• Molecular Weight: 537.70
• Purity: ≥95%
• Synonyms: Tauro-β-muricholate;TβMCA
• Storage: -20°C
• IUPAC Name: sodium;2-[[(4R)-4-[(3R,5R,6S,7R,8S,9S,10R,13R,14S,17R)-3,6,7-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]ethanesulfonate
• InChI: InChI=1S/C26H45NO7S.Na/c1-15(4-7-21(29)27-12-13-35(32,33)34)17-5-6-18-22-19(9-11-25(17,18)2)26(3)10-8-16(28)14-20(26)23(30)24(22)31;/h15-20,22-24,28,30-31H,4-14H2,1-3H3,(H,27,29)(H,32,33,34);/q;+1/p-1/t15-,16-,17-,18+,19+,20+,22+,23+,24-,25-,26-;/m1./s1
• InChIKey: NYXROOLWUZIWRB-GPHZYVDLSA-M
• SMILES: C[C@H](CCC(NCCS([O-])(=O)=O)=O)[C@@]1([H])CC[C@@]2([H])[C@]3([H])[C@@H](O)[C@@H](O)[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@@]21C.[Na+]

Tauro-β-muricholic Acid (Sodium Salt)(CAT: R066738) is a bile acid conjugate commonly found in rodents, particularly mice and rats. It is a taurine-conjugated form of β-muricholic acid, a type of bile acid involved in the digestion and absorption of fats and fat-soluble vitamins in the small intestine. The sodium salt form enhances its solubility in aqueous environments, making it suitable for various biochemical and physiological studies. Tauro-β-muricholic Acid is of interest in research due to its role in cholesterol metabolism, gut microbiota interactions, and its potential protective effects against liver diseases. It is also studied for its influence on the regulation of bile acid receptors such as FXR (Farnesoid X Receptor), which are key regulators of bile acid synthesis and metabolism.