Tautomycetin

• CAT Number: R014620
• CAS Number: 119757-73-2
• Molecular Formula: C33H50O10
• Molecular Weight: 606.75
• Purity: ≥95%
• Synonyms: (βR)-2,5-Dihydro-β-hydroxy-4-methyl-2,5-dioxo-3-furanpropanoic Acid (1R,2S,6S,7S,10S,12R,15E)-16-Ethyl-3,7-dihydroxy-1,2,6,10,12-pentamethyl-5,14-dioxo-15,17-octadecadien-1-yl Ester
• Target: Protein Ser/Thr Phosphatases
• Solubility: Soluble in DMSO > 10 mM
• Storage: Desiccate at -20C
• IUPAC Name: [(16E)-17-ethyl-4,8-dihydroxy-3,7,11,13-tetramethyl-6,15-dioxononadeca-16,18-dien-2-yl] 3-hydroxy-3-(4-methyl-2,5-dioxofuran-3-yl)propanoate
• InChI: InChI=1S/C33H50O10/c1-9-24(10-2)15-25(34)14-19(4)13-18(3)11-12-26(35)21(6)28(37)16-27(36)20(5)23(8)42-30(39)17-29(38)31-22(7)32(40)43-33(31)41/h9,15,18-21,23,26-27,29,35-36,38H,1,10-14,16-17H2,2-8H3/b24-15-
• InChIKey: VAIBGAONSFVVKI-IWIPYMOSSA-N
• SMILES: CC/C(=C\C(=O)CC(C)CC(C)CCC(C(C)C(=O)CC(C(C)C(C)OC(=O)CC(C1=C(C(=O)OC1=O)C)O)O)O)/C=C

Tautomycetin(Cat No.:R014620) is a polyketide natural product originally isolated from the bacterium Streptomyces sp. It is known for its potent immunosuppressive and antitumor properties. Tautomycetin exerts its biological effects by inhibiting protein phosphatases, particularly PP1 and PP2A, which are key regulators of cellular processes such as cell cycle progression, apoptosis, and signal transduction. Due to its ability to modulate these pathways, tautomycetin is of interest in cancer research and as a potential therapeutic agent for immune-related diseases. Additionally, it serves as a valuable tool for studying phosphatase-related signaling mechanisms in cells.