Tazarotenic Acid

• CAT Number: R013214
• CAS Number: 118292-41-4
• Molecular Formula: C19H17NO2S
• Molecular Weight: 323.41
• Purity: ≥95%
• Synonyms: 6-[2-(3,4-Dihydro-4,4-dimethyl-2H-1-benzothiopyran-6-yl)ethynyl]-3-pyridinecarboxylic Acid; AGN 190299; ??
• Target: Drug Metabolite
• Storage: -20°C
• IUPAC Name: 6-[2-(4,4-dimethyl-2,3-dihydrothiochromen-6-yl)ethynyl]pyridine-3-carboxylic acid
• InChI: InChI=1S/C19H17NO2S/c1-19(2)9-10-23-17-8-4-13(11-16(17)19)3-6-15-7-5-14(12-20-15)18(21)22/h4-5,7-8,11-12H,9-10H2,1-2H3,(H,21,22)
• InChIKey: IQIBKLWBVJPOQO-UHFFFAOYSA-N
• SMILES: CC1(CCSC2=C1C=C(C=C2)C#CC3=NC=C(C=C3)C(=O)O)C

Tazarotenic acid(CAT: R013214) is the active metabolite of tazarotene, a topical retinoid used to treat skin conditions like psoriasis, acne, and sun damage. As a retinoid, tazarotenic acid works by binding to retinoic acid receptors (RARs) in the skin, which helps to regulate cell growth, reduce inflammation, and normalize skin shedding. This action promotes the turnover of skin cells and reduces the formation of plaques in psoriasis or acne lesions. Tazarotenic acid is considered highly effective in improving skin texture and tone, though it may cause irritation or dryness as side effects in some individuals during treatment.