Tazarotenic Acid Sulfone-d8

• CAT Number: R021884
• CAS Number: NA
• Molecular Formula: C₁₉H₉D₈NO₄S
• Molecular Weight: 363.46
• Purity: ≥95%
• Synonyms: 6-[(3,4-dihydro-4,4-dimethyl-1,1-dioxido-2H-1-benzothiopyran-6-yl)ethynyl]-3-Pyridinecarboxylic acid-d8; 6-((4,4-dimethyl-1,1-dioxidothiochroman-6-yl)ethynyl)nicotinic acid-d8; Tazarotenic Acid Sulphone-d8
• Storage: Store at +4C
• IUPAC Name: 6-[2-[2,2-dideuterio-1,1-dioxo-4,4-bis(trideuteriomethyl)-3H-thiochromen-6-yl]ethynyl]pyridine-3-carboxylic acid
• InChI: InChI=1S/C19H17NO4S/c1-19(2)9-10-25(23,24)17-8-4-13(11-16(17)19)3-6-15-7-5-14(12-20-15)18(21)22/h4-5,7-8,11-12H,9-10H2,1-2H3,(H,21,22)/i1D3,2D3,10D2
• InChIKey: SNSJBSLKHBITIU-YXDKRSHTSA-N
• SMILES: [2H]C1(CC(C2=C(S1(=O)=O)C=CC(=C2)C#CC3=NC=C(C=C3)C(=O)O)(C([2H])([2H])[2H])C([2H])([2H])[2H])[2H]

Tazarotenic Acid Sulfone-d8 is a deuterated analog of tazarotenic acid sulfone, where eight hydrogen atoms are replaced with deuterium. This compound is primarily utilized in pharmacokinetic and drug metabolism studies as an internal standard in mass spectrometry. The deuterium labeling allows for the precise differentiation and quantification of the compound in biological samples, aiding in the accurate analysis of tazarotene metabolism and its derivatives. Tazarotenic Acid Sulfone-d8 is particularly valuable in pharmaceutical research for studying the metabolic pathways, distribution, and excretion of tazarotene, a retinoid used in the treatment of psoriasis and acne.