For research use only. Not for therapeutic Use.
TBDMS-PEG4-OH (CAT: I015616) is a PEG-based PROTAC linker that can be utilized in the synthesis of PROTACs. PROTACs, or proteolysis-targeting chimeras, are innovative molecules designed to target specific proteins for degradation within cells. The TBDMS-PEG4-OH linker can connect different functional groups, enabling the creation of PROTAC compounds that can recruit target proteins for ubiquitin-mediated degradation through the cell’s proteasome system.
| Catalog Number | I015616 |
| CAS Number | 134179-40-1 |
| Molecular Formula | C₁₄H₃₂O₅Si |
| Purity | ≥95% |
| Target | PROTAC Linkers |
| Reference | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
