TC AQP1 1

• CAT Number: I011190
• CAS Number: 37710-81-9
• Molecular Formula: C12H10O4
• Molecular Weight: 218.21
• Purity: ≥95%
• Synonyms: (E)-3-[3-[(E)-2-carboxyethenyl]phenyl]prop-2-enoic acid
• InChI: InChI=1S/C12H10O4/c13-11(14)6-4-9-2-1-3-10(8-9)5-7-12(15)16/h1-8H,(H,13,14)(H,15,16)/b6-4+,7-5+
• InChIKey: KRXUBZPHAPGHPE-YDFGWWAZSA-N
• SMILES: C1=CC(=CC(=C1)C=CC(=O)O)C=CC(=O)O

TC AQP1 1 (m-Phenylenediacrylic acid) is a potent AQP1 inhibitor. TC AQP1 1 inhibits AQP1-mediated water flux in oocytes, with an IC50 of 8 μM[1].

Reference

[1]. Salman MM, et al. Recent breakthroughs and future directions in drugging aquaporins. Trends Pharmacol Sci. 2022 Jan;43(1):30-42.
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