TC ASK 10

• CAT Number: R061891
• CAS Number: 1005775-56-3
• Molecular Formula: C21H23Cl2N5O
• Molecular Weight: 432.34
• Purity: ≥95%
• Synonyms: 4-(1,1-Dimethylethyl)-N-[6-(1H-imidazol-1-yl)imidazo[1,2-a]pyridin-2-yl]-,benzamide Dihydrochloride;?4-tert-Butyl-N-[6-(1H-imidazol-1-yl)imidazo[1,2-a]pyridin-2-yl]benzamide Dihydrochloride
• Target: ASK1
• Solubility: Soluble in DMSO > 10 mM
• Storage: Desiccate at RT
• IUPAC Name: 4-tert-butyl-N-(6-imidazol-1-ylimidazo[1,2-a]pyridin-2-yl)benzamide;dihydrochloride
• InChI: InChI=1S/C21H21N5O.2ClH/c1-21(2,3)16-6-4-15(5-7-16)20(27)24-18-13-26-12-17(8-9-19(26)23-18)25-11-10-22-14-25;;/h4-14H,1-3H3,(H,24,27);2*1H
• InChIKey: IKKLFEDUYFZNBO-UHFFFAOYSA-N
• SMILES: CC(C)(C)C1=CC=C(C=C1)C(=O)NC2=CN3C=C(C=CC3=N2)N4C=CN=C4.Cl.Cl

TC ASK 10（Cat No.:R061891）is a selective inhibitor of apoptosis signal-regulating kinase 1 (ASK1), a key component of the MAPK signaling pathway involved in cellular responses to stress, inflammation, and apoptosis. By inhibiting ASK1, TC ASK 10 effectively blocks downstream activation of JNK and p38 MAPK, reducing oxidative stress-induced apoptosis and inflammatory cytokine production. It has applications in studying cardiovascular diseases, neurodegenerative disorders, and other conditions where ASK1-mediated signaling contributes to pathology. TC ASK 10 is a valuable research tool for exploring ASK1’s role in cell survival and stress response, with implications for developing therapeutic strategies.