TCEP-d12 Hydrochloride

• CAT Number: R010157
• CAS Number: 1189959-10-1
• Molecular Formula: C9H16ClO6P
• Molecular Weight: 298.718
• Purity: ≥95%
• Synonyms: 3,3’,3’’-Phosphinidynetrispropanoic Acid-d12; Tris(2-carboxyethyl)phosphine-d12 Hydrochloride; Tris(carboxyethyl)phosphine-d12 Hydrochloride; ?
• Storage: Store at -20C
• IUPAC Name: 3-bis(2-carboxy-1,1,2,2-tetradeuterioethyl)phosphanyl-2,2,3,3-tetradeuteriopropanoic acid;hydrochloride
• InChI: InChI=1S/C9H15O6P.ClH/c10-7(11)1-4-16(5-2-8(12)13)6-3-9(14)15;/h1-6H2,(H,10,11)(H,12,13)(H,14,15);1H/i1D2,2D2,3D2,4D2,5D2,6D2
• InChIKey: PBVAJRFEEOIAGW-XDVLEJMRSA-N
• SMILES: [2H]C([2H])(C(=O)O)C([2H])([2H])P(C([2H])([2H])C([2H])([2H])C(=O)O)C([2H])([2H])C([2H])([2H])C(=O)O.Cl

TCEP-d12 Hydrochloride is a deuterium-labeled version of tris(2-carboxyethyl)phosphine hydrochloride, a potent reducing agent commonly used in biochemical and molecular biology applications. The deuterium atoms enhance its detectability and allow for detailed studies of its reducing properties and interaction mechanisms using mass spectrometry and NMR spectroscopy. TCEP-d12 is essential for investigating redox reactions, protein folding, and disulfide bond reduction in proteins. It provides a stable and effective alternative to other reducing agents, aiding in the development of protocols for protein analysis, enzyme activity assays, and the study of cellular redox states in various research fields.