For research use only. Not for therapeutic Use.
TD-139 (CAT: I009529) is a galectin-3 inhibitor that shows potential for the treatment of idiopathic pulmonary fibrosis (IPF). Galectin-3 is a protein involved in the progression of fibrosis, including the excessive accumulation of scar tissue in the lungs seen in IPF. TD-139 works by specifically targeting and inhibiting the activity of galectin-3, which can help prevent or reduce fibrosis in the lungs. By blocking galectin-3, TD-139 may have a therapeutic effect in slowing down or reversing the progression of IPF, offering a potential treatment option for this debilitating lung disease.
| Catalog Number | I009529 |
| CAS Number | 1450824-22-2 |
| Synonyms | TD-139; TD139; TD 139;(2R,2/’R,3R,3/’R,4S,4/’S,5R,5/’R,6S,6/’S)-6,6/’-thiobis(4-(4-(3-fluorophenyl)-1H-1,2,3-triazol-1-yl)-2-(hydroxymethyl)tetrahydro-2H-pyran-3,5-diol) |
| Molecular Formula | C26H48N8O2 |
| Purity | 98% |
| Target | Galectin |
| Solubility | Soluble in DMSO |
| Appearance | Solid powder |
| Storage | 0 - 4 °C for short term, or -20 °C for long term |
| InChI | InChI=1S/C28H30F2N6O8S/c29-15-5-1-3-13(7-15)17-9-35(33-31-17)21-23(39)19(11-37)43-27(25(21)41)45-28-26(42)22(24(40)20(12-38)44-28)36-10-18(32-34-36)14-4-2-6-16(30)8-14/h1-10,19-28,37-42H,11-12H2/t19-,20-,21+,22+,23+,24+,25-,26-,27+,28+/m1/s1 |
| InChIKey | YGIDGBAHDZEYMT-MQFIMZJJSA-N |
| SMILES | O[C@H]([C@@H](N1N=NC(C2=CC=CC(F)=C2)=C1)[C@H]([C@@H](CO)O3)O)[C@@H]3S[C@H]4[C@@H]([C@@H](N5N=NC(C6=CC=CC(F)=C6)=C5)[C@H]([C@@H](CO)O4)O)O |
| Reference | <br /> |
