TDO-IN-1

• CAT Number: I043119
• CAS Number: 2490672-92-7
• Molecular Formula: C16H13F3N4O2
• Molecular Weight: 350.30
• Purity: ≥95%
• Synonyms: N-[(4-methyl-2-nitrophenyl)methyl]-6-(trifluoromethyl)-1H-indazol-4-amine
• InChI: InChI=1S/C16H13F3N4O2/c1-9-2-3-10(15(4-9)23(24)25)7-20-13-5-11(16(17,18)19)6-14-12(13)8-21-22-14/h2-6,8,20H,7H2,1H3,(H,21,22)
• InChIKey: FIFXIQQUXZVXNB-UHFFFAOYSA-N
• SMILES: CC1=CC(=C(C=C1)CNC2=CC(=CC3=C2C=NN3)C(F)(F)F)[N+](=O)[O-]

TDO-IN-1（Cat No.:I043119）is a small molecule inhibitor that specifically targets Tryptophan 2,3-Dioxygenase (TDO), an enzyme involved in the metabolism of tryptophan along the kynurenine pathway. TDO-IN-1 inhibits TDO activity, potentially modulating immune responses and mitigating tumor growth, as TDO is often upregulated in cancers and autoimmune diseases. By blocking TDO, the compound may reduce kynurenine production, which has immunosuppressive effects. TDO-IN-1 has been explored for its therapeutic potential in cancer and inflammatory diseases, offering a promising approach for modulating immune function and improving cancer treatment outcomes.