For research use only. Not for therapeutic Use.
TEAD-IN-2 is a novel, orally active inhibitor of transcriptional enhancer associate domain (TEAD) and modulates TEAD by ubiquitination and/or degradation by compounds. TEAD-IN-2 can be used for the research of a variety of diseases, disorders or conditions associated with TEAD[1].
| Catalog Number | I043436 |
| CAS Number | 2563849-97-6 |
| Synonyms | 3-bromo-5-[1-[[4-(trifluoromethyl)phenyl]methyl]piperidin-4-yl]-4,5-dihydro-1,2-oxazole |
| Molecular Formula | C16H18BrF3N2O |
| Purity | ≥95% |
| InChI | InChI=1S/C16H18BrF3N2O/c17-15-9-14(23-21-15)12-5-7-22(8-6-12)10-11-1-3-13(4-2-11)16(18,19)20/h1-4,12,14H,5-10H2 |
| InChIKey | PGYSFRYXGVNVIO-UHFFFAOYSA-N |
| SMILES | C1CN(CCC1C2CC(=NO2)Br)CC3=CC=C(C=C3)C(F)(F)F |
| Reference | [1]. Alfredo C. Castro, et al. Preparation of heterocyclic compounds as TEAD degraders and uses thereof. Patent wo2022120355A1. |
