For research use only. Not for therapeutic Use.
Tedizolid Phosphate(Cat No.:A000045) is an oxazolidinone-class antibiotic used to treat acute bacterial skin and skin structure infections (ABSSSI), particularly those caused by Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA). Tedizolid Phosphate is a prodrug that is rapidly converted into its active form, Tedizolid, after oral or intravenous administration. It inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit, preventing the formation of a functional ribosome. Tedizolid Phosphate is known for its potency, favorable safety profile, and once-daily dosing regimen, making it a preferred option in certain clinical settings over other antibiotics like linezolid. Its reduced risk of myelosuppression and shorter treatment duration also enhance its therapeutic appeal.
Catalog Number | A000045 |
CAS Number | 856867-55-5 |
Synonyms | TR-701FA |
Molecular Formula | C17H16FN6O6P |
Purity | ≥95% |
Target | Bacterial |
Storage | Store at -20°C |
IUPAC Name | [(5R)-3-[3-fluoro-4-[6-(2-methyltetrazol-5-yl)pyridin-3-yl]phenyl]-2-oxo-1,3-oxazolidin-5-yl]methyl dihydrogen phosphate |
InChI | InChI=1S/C17H16FN6O6P/c1-23-21-16(20-22-23)15-5-2-10(7-19-15)13-4-3-11(6-14(13)18)24-8-12(30-17(24)25)9-29-31(26,27)28/h2-7,12H,8-9H2,1H3,(H2,26,27,28)/t12-/m1/s1 |
InChIKey | QCGUSIANLFXSGE-GFCCVEGCSA-N |
SMILES | CN1N=C(N=N1)C2=NC=C(C=C2)C3=C(C=C(C=C3)N4C[C@@H](OC4=O)COP(=O)(O)O)F |