For research use only. Not for therapeutic Use.
Tefibazumab is a humanized IgG1κ monoclonal antibody that binds to the surface-expressed adhesion protein clumping factor A. Tefibazumab can be used for the research of serious Staphylococcus aureus infections[1][2].
Tefibazumab has a variable antigen binding region composed of human (>98%) and murine (<2%) amino acid sequences. Tefibazumab specifically recognizes and has a high affinity for ClfA expressed by S. aureus[2].
| Catalog Number | I042118 |
| CAS Number | 521079-87-8 |
| Purity | ≥95% |
| Reference | [1]. pharmacokinetics of tefibazumab to placebo for treatment of Staphylococcus aureus bacteremia. Antimicrob Agents Chemother. 2006 Aug;50(8):2751-5. [2]. Reilley S, et, al. Open-label, dose escalation study of the safety and pharmacokinetic profile of tefibazumab in healthy volunteers. Antimicrob Agents Chemother. 2005 Mar;49(3):959-62. |
