For research use only. Not for therapeutic Use.
Tegaserod maleate (Cat.No:I002438) is a medication used for the management of irritable bowel syndrome with constipation (IBS-C) in women. It acts as a selective serotonin receptor agonist, enhancing gastrointestinal motility and reducing symptoms of constipation and abdominal discomfort. Tegaserod maleate provides relief for IBS-C patients and has been approved for specific indications in several countries.
| Catalog Number | I002438 |
| CAS Number | 189188-57-6 |
| Synonyms | (E)-2-((Z)-(5-methoxy-3H-indol-3-ylidene)methyl)-N/’-pentylhydrazinecarboximidamide maleate |
| Molecular Formula | C16H23N5O • C4H4O4 |
| Purity | ≥95% |
| Target | Neuronal Signaling |
| Solubility | DMSO: ≥ 35 mg/mL |
| Storage | Store at +4C |
| InChIKey | CPDDZSSEAVLMRY-FEQFWAPWSA-N |
| Reference | </br>1:Estimation of tegaserod maleate by differential pulse polarography. Rajput SJ, Raj HA.Indian J Pharm Sci. 2009 Jan;71(1):50-2. doi: 10.4103/0250-474X.51956. PMID: 20177456 Free PMC Article</br>2:In vitro and in vivo evaluation of tegaserod maleate pH-dependent tablets. Zhang SQ, Thumma S, Chen GH, Deng WB, Repka MA, Li SM.Eur J Pharm Biopharm. 2008 May;69(1):247-54. Epub 2007 Oct 25. PMID: 18037278 </br>3:Tegaserod maleate in the treatment of irritable bowel syndrome: a clinical review. Rivkin A.Clin Ther. 2003 Jul;25(7):1952-74. Review. PMID: 12946544 </br>4:Tegaserod maleate (Zelnorm) for IBS with constipation. [No authors listed]Med Lett Drugs Ther. 2002 Sep 16;44(1139):79-80. No abstract available. PMID: 12237618 |
