Telbivudine

• CAT Number: A000826
• CAS Number: 3424-98-4
• Molecular Formula: C10H14N2O5
• Molecular Weight: 242.23
• Purity: ≥95%
• Synonyms: Epavudine; Beta-L-Thymidine; 2/’-Deoxy-L-thymidine; Tyzeka; Telbivudin
• Target: HBV
• Solubility: >11.9mg/mL in DMSO
• Storage: -20°C
• IUPAC Name: 1-[(2S,4R,5S)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
• InChI: InChI=1S/C10H14N2O5/c1-5-3-12(10(16)11-9(5)15)8-2-6(14)7(4-13)17-8/h3,6-8,13-14H,2,4H2,1H3,(H,11,15,16)/t6-,7+,8+/m1/s1
• InChIKey: IQFYYKKMVGJFEH-CSMHCCOUSA-N
• SMILES: CC1=CN(C(=O)NC1=O)[C@@H]2C[C@H]([C@@H](O2)CO)O

Telbivudine（Cat No.:A000826）is a nucleoside analog antiviral medication used to treat chronic hepatitis B virus (HBV) infections. It inhibits HBV replication by incorporating into the viral DNA during replication, causing chain termination. Telbivudine is highly effective in reducing viral load and improving liver function, making it a valuable option for managing chronic HBV and preventing disease progression to cirrhosis or liver cancer. Its good safety profile and potent antiviral activity make it a key therapeutic agent for long-term HBV management in clinical practice and research.

Reference

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lactic acidosis, and multiple organ failure during telbivudine treatment for
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3: Shi H, Han Z, Liu J, Xue J, Zhang S, Zhu Z, Xia J, Huang M. Comparing Efficacy
of Lamivudine, Adefovir Dipivoxil, Telbivudine, and Entecavir in Treating
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8: Liu J, Yao N, Zhao Y. Improvement of telbivudine on renal function and massive
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9: Shang J, Wen Q, Wang CC, Liu K, Bai L, Tang H. Safety and efficacy of
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