For research use only. Not for therapeutic Use.
Telithromycin(Cat No.:M128936) is a ketolide antibiotic used to treat respiratory tract infections. It works by inhibiting bacterial protein synthesis, specifically targeting the 50S subunit of the bacterial ribosome. Telithromycin is effective against a variety of bacteria, including Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis. It is commonly used to treat community-acquired pneumonia, acute exacerbations of chronic bronchitis, and sinusitis. However, telithromycin has been associated with rare but serious side effects, including liver toxicity and exacerbation of myasthenia gravis.
Catalog Number | M128936 |
CAS Number | 173838-31-8 |
Synonyms | Unii-ki8H7H19wl |
Molecular Formula | C43H65N5O10 |
Purity | ≥95% |
Storage | Store at +4C |
IUPAC Name | (1S,2R,5R,7R,8R,9R,11R,13R,14S)-8-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-2-ethyl-9-methoxy-1,5,7,9,11,13-hexamethyl-15-[4-(4-pyridin-3-ylimidazol-1-yl)butyl]-3,17-dioxa-15-azabicyclo[12.3.0]heptadecane-4,6,12,16-tetrone |
InChI | InChI=1S/C43H65N5O10/c1-12-33-43(8)37(48(41(53)58-43)19-14-13-18-47-23-31(45-24-47)30-16-15-17-44-22-30)27(4)34(49)25(2)21-42(7,54-11)38(28(5)35(50)29(6)39(52)56-33)57-40-36(51)32(46(9)10)20-26(3)55-40/h15-17,22-29,32-33,36-38,40,51H,12-14,18-21H2,1-11H3/t25-,26-,27+,28+,29-,32+,33-,36-,37+,38-,40+,42-,43-/m1/s1 |
InChIKey | LJVAJPDWBABPEJ-XZVSULPPSA-N |
SMILES | CCC1C2(C(C(C(=O)C(CC(C(C(C(=O)C(C(=O)O1)C)C)OC3C(C(CC(O3)C)N(C)C)O)(C)OC)C)C)N(C(=O)O2)CCCCN4C=C(N=C4)C5=CN=CC=C5)C |